Journal Articles

• Costello KE, Felson DT, Jafarzadeh SR, Guermazi A, Roemer FW, Segal NA, Lewis CE, Nevitt MC, Lewis CL, Kolachalama VB, Kumar D. Tibiofemoral cartilage worsening in persons without advanced radiographic osteoarthritis: A machine learning analysis of gait and physical activity in the Multicenter Osteoarthritis Study. British Journal of Sports Medicine [Epub Mar 2023, Preprint July 2022]; doi: 10.1136/bjsports-2022-106142.
• Rose MJ, LaValley MP, Jafarzadeh SR, Costello KE, Shah N, Lee S, Rabasa G, Borrelli B, Messier SP, Neogi T, Kumar D. Impact of COVID-19 pandemic on physical activity, pain, mood, and sleep in adults with knee osteoarthritis. Journal for the Measurement of Physical Behaviour, 5(4): 294-298, 2022 [Epub Dec 2022]; doi: 10.1123/jmpb.2022-0019.
• Shah N, Costello KE, Mehta A, Kumar D. Applications of digital health technologies in knee osteoarthritis: narrative review. JMIR Rehabilitation and Assistive Technologies 9(2): e33489, 2022 [Preprint Sept 2021]; doi: 10.2196/33489.
• Rose M, Costello KE, Eigenbrot S, Torabian KA, Kumar D. Inertial measurement units and application for remote healthcare in hip and knee osteoarthritis: narrative review. JMIR Rehabilitation and Assistive Technologies 9(2): e33521, 2022 [Preprint Sept 2021]; doi: 10.2196/33521.
• Costello KE, Astephen Wilson JL, Hubley-Kozey CL. Association of low physical activity levels with gait patterns considered “at risk” for clinical knee osteoarthritis progression. Arthritis Care & Research Open Rheumatology 3(11): 753-763, 2021 [Epub Oct 2021]; doi: 10.1002/acr2.11319.
• Hatfield GL, Costello KE, Astephen Wilson JL, Stanish WD, Hubley-Kozey CL. The association between knee joint muscle activation and knee joint moment patterns during walking in moderate medial compartment knee osteoarthritis: implications for secondary prevention. Archives of Physical Medicine and Rehabilitation 102(10): 1910-1917, 2021 [Epub July 2021]; doi: 10.106/j.apmr.2021.03.038.
• Costello KE, Felson DT, Neogi T, Segal NA, Lewis CE, Gross KD, Nevitt MC, Lewis CL, Kumar D. Ground reaction force patterns in knees with and without radiographic osteoarthritis and pain: descriptive analyses of a large cohort (the Multicenter Osteoarthritis Study). Osteoarthritis & Cartilage 29(8):1138-1146, 2021 [Epub Mar 2021]; doi: 10.1016/j.joca.2021.03.009.
• Mobasheri A, Costello KE. Podcasting: an innovative tool for enhanced osteoarthritis education and research dissemination. Osteoarthritis & Cartilage Open 3(1); 2021 [Epub Dec 2020]; doi: 10.1016/j.ocarto.2020.100130.
• Costello KE, Eigenbrot S, Geronimo A, Guermazi A, Felson DT, Richards J, Kumar D. Quantifying varus thrust in knee osteoarthritis using wearable inertial sensors: a proof of concept. Clinical Biomechanics 80, 2020 (Online ahead of print); doi: 10.1016/j.clinbiomech.2020.105232.
• Espinosa SE, Costello KE, Souza RB, Kumar D. Lower knee extensor and flexor strength is associated with varus thrust in people with knee osteoarthritis. Journal of Biomechanics 107(23), 2020 [Epub May 2020]; doi: 10.1016/j.jbiomech.2020.109865.
• Hatfield GL, Costello KE, Astephen Wilson JL, Stanish WD, Hubley-Kozey CL. Baseline gait muscle activation patterns differ for osteoarthritis patients who undergo total knee arthroplasty 5 – 8 years later and those who do not. Arthritis Care & Research 73(4):549-558, 2021 [Epub Jan 2020]; doi: 10.1002/acr.24143.
• Costello KE, Astephen Wilson JL, Stanish WD, Urquhart N, Hubley-Kozey CL. Differences in baseline joint moments and muscle activation patterns associated with knee osteoarthritis progression when defined using a clinical versus a structural outcome. Journal of Applied Biomechanics 36(1): 39-51, 2020; doi: 10.1123/jab.2019-0127.
• Costello KE, Astephen Wilson JL, Hubley-Kozey CL. Single versus multiple monitoring periods for accelerometer-measured physical activity in knee osteoarthritis and asymptomatic controls. Journal for the Measurement of Physical Behaviour 3(1):29-38, 2020; doi: 10.1123/jmpb.2019-0010.
• Jansson KS, Costello KE, O’Brien L, Wijdicks CA, LaPrade RF. A historical perspective of PCL Bracing. Knee Surg Sports Traumatol Arthrosc 21(5): 1064-1070, 2013 [Epub May 2012]; doi: 10.1007/s00167-012-2048-9.
• Costello KE, Matrangola SL, Madigan ML. Independent effects of adding weight and inertia on balance during quiet standing. Biomed Eng Online 11(20), 2012; doi: 10.1186/1475-925X-11-20.
• Costello KE, Guilak F, Setton LA, Griffin TM. Locomotor activity and gait in aged mice deficient for type IX collagen. J Appl Physiol 109: 211-218, 2010; doi: 10.1152/japplphysiol.00056.2010.

Conference Proceedings

2023

• Costello KE, Felson DT, Jafarzadeh SR, Segal N, Lewis CE, Nevitt M, Kolachalama VB, Kumar D. Gait and physical activity predictors of knee replacement in the Multicenter Osteoarthritis Study: a machine learning analysis. Osteoarthritis Research Society International World Congress on Osteoarthritis, Denver, CO, USA. March 17^th-20^th, 2023.
• Corrigan P, Lewis CL, Costello KE, Guermazi A, Roemer F, Kumar D, Felson DT, Bacon KL, Neogi T, LaValley MP, Nevitt MC, Lewis CE, Torner JC, Stefanik JJ. Asymmetric ground reaction forces while walking are not associated with unilateral to bilateral knee osteoarthritis progression: The MOST Study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Denver, CO, USA. March 17^th-20^th, 2023.
• Kumar D, Wang N, Torabian K, Lee S, Frey-Law L, Carlesso LC, Hausdorff JM, Gazit E, Costello KE, Lewis CL, Stefanik JJ, Segal NA, Lewis CE, Nevitt MC, Neogi T. Gait and changes in nociceptive function over 2-years in people with knee osteoarthritis: the Multicenter Osteoarthritis Study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Denver, CO, USA. March 17^th-20^th, 2023.
• Costello KE. A machine learning approach to investigate the role of gait and physical activity in knee osteoarthritis progression. Orthopaedic Research Society Annual Meeting, Research Interest Group ‘Bridging disciplines to find solutions for osteoarthritis’, Dallas, TX, USA. February 10^th-14^th, 2023. [Invited talk]

2022

• Corrigan P, Lewis CL, Costello KE, Guermazi A, Roemer F, Kumar D, Felson DT, Bacon KL, Neogi T, LaValley MP, Nevitt MC, Lewis CE, Torner, JC, Stefanik JJ. Three-dimensional ground reaction force symmetry metrics largely fail to explain cartilage worsening in the contralateral knee in persons with unilateral knee osteoarthritis: The Multicenter Osteoarthritis Study. American College of Rheumatology Convergence, Philadelphia, PA, USA. November 10^th-14^th, 2022. 
• Costello KE, Felson DT, Jafarzadeh SR, Segal N, Lewis CE, Nevitt M, Kolachalama VB, Kumar D. Gait and physical activity predictors of knee replacement: a machine learning analysis in the Multicenter Osteoarthritis Study. American College of Rheumatology Convergence, Philadelphia, PA, USA. November 10^th-14^th, 2022. 
• Costello KE, Guermazi A, Roemer FW, Lewis CE, Torner JC, Nevitt MC, Felson DT, Jafarzadeh SR. Characterizing the combined effect of physical activity measures on structural progression of OA: The Multicenter Osteoarthritis Study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Berlin, Germany. April 7^th-10^th, 2022.
• Lee S, Neogi T, Costello KE, Shah N, Rose MJ, Friscia BS, Torabian KA, Gheller M, Aoyagi K, Kumar D. Association of conditioned pain modulation with exercise-induced hypoalgesia in knee osteoarthritis. Osteoarthritis Research Society International World Congress on Osteoarthritis, Berlin, Germany. April 7^th-10^th, 2022.
• Kumar D, Costello KE, Shah N, Neogi T, Lee S, Rose MJ, Manal KT, Borrelli B, Messier S, LaValley MP. Mindful walking in knee osteoarthritis: a feasibility randomized controlled trial. Osteoarthritis Research Society International World Congress on Osteoarthritis, Berlin, Germany. April 7^th-10^th, 2022.
• Mehta A, Costello KE, Rose M, Lee S, Frey Law LA, Aoyagi K, Neogi T, Kumar D. Association between impaired exercise induced hypoalgesia and physical activity in people with knee osteoarthritis. American Physical Therapy Association Combined Sections Meeting, San Antonio, TX, USA. February 2^nd – 5^th, 2022.

2021

• Costello KE, Felson DT, Jafarzadeh SR, Segal N, Lewis CE, Nevitt M, Lewis CL, Kolachalama VB, Kumar D. Using machine learning to predict medial knee cartilage worsening over 2 years using gait and physical activity: the MOST Study. American College of Rheumatology Convergence. November 5^th – 9^th, 2021. [Poster tour selection]
• Rose M, LaValley MP, Jafarzadeh SR, Costello KE, Shah N, Lee S, Rabasa G, Borrelli B, Messier S, Neogi T, Kumar D. Impact of COVID-19 pandemic on physical activity, pain, mood, and sleep in adults with knee osteoarthritis. Osteoarthritis Research Society International World Congress on Osteoarthritis, Virtual. April 29^th – May 1^st, 2021.
• Lee S, Neogi T, Eigenbrot S, Stefanik JJ, Costello KE, Kumar D. Mechanical temporal summation is associated with greater muscle co-contraction during walking in knee osteoarthritis. Osteoarthritis Research Society International World Congress on Osteoarthritis, Virtual. April 29^th – May 1^st, 2021.

2020

• Costello KE, Felson DT, Kolachalama V, Lewis CL, Liu F, Gross KD, Segal NA, Lewis CE, Nevitt MC, Kumar D. Flatter ground reaction force patterns are associated with incident knee pain over two years: the Multicenter Osteoarthritis Study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Vienna, Austria. April 30^th – May 3^rd, 2020. (Conference Cancelled due to COVID-19 pandemic).
• Kumar D, Costello KE, Segal N, Williams GN, Gross D, Lewis CE, Nevitt MC, Lewis CL, Felson DT. Lower quadriceps power is related with less dynamic ground reaction force patterns during walking in females: the Multicenter Osteoarthritis Study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Vienna, Austria. April 30^th – May 3^rd, 2020. (Conference Cancelled due to COVID-19 pandemic).

2019

• Costello KE, Felson DT, Neogi T, Segal N, Lewis CE, Gross KD, Nevitt M, Lewis CL, Kumar D. Ground reaction force patterns in knees with and without pain and radiographic osteoarthritis: descriptive analyses from a large cohort study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Toronto, ON, Canada. May 2^nd – 5^th, 2019. [Poster tour selection]
• Kumar D, Costello KE, Neogi T, Lewis CE, Segal N, Gross D, Nevitt M, Lewis CL, Felson DT. Sex and race related differences in ground reaction forces during walking and interactions with knee pain and osteoarthritis in a large cohort. Osteoarthritis Research Society International World Congress on Osteoarthritis, Toronto, ON, Canada. May 2^nd – 5^th, 2019.
• Kumar D, Costello KE, Chan D, Ma, CB, Li X. Longitudinal changes in gait waveforms with ACL reconstruction. Osteoarthritis Research Society International World Congress on Osteoarthritis, Toronto, ON, Canada. May 2^nd – 5^th, 2019.
• Costello KE, Astephen Wilson JL, Hubley-Kozey CL. Low physical activity levels in knee osteoarthritis associated with “at risk” gait patterns. Osteoarthritis Research Society International World Congress on Osteoarthritis, Toronto, ON, Canada. May 2^nd – 5^th, 2019. [Poster tour selection]

2018

• Costello KE, Astephen Wilson JL, Stanish W, Hubley-Kozey CL. A comparison of modeling clinical knee osteoarthritis progression using knee joint moments, muscle activation patterns, descriptive data, or a combination. 20^th Biennial Meeting of the Canadian Society for Biomechanics, Halifax, NS, Canada. August 14^th – 17^th, 2018.
• Costello KE, Astephen Wilson JL, Hubley-Kozey CL. Physical activity accumulated in different intensities in women, but not men, with osteoarthritis compared to asymptomatic controls. Canadian Bone and Joint Conference, London, ON, Canada. May 10^th – 12^th, 2018.
• Costello KE, Astephen Wilson JL, Hubley-Kozey CL. Differences in using a single week of accelerometer data versus averaging multiple weeks in individuals with knee osteoarthritis and asymptomatic controls: implications for cumulative load calculations. Osteoarthritis Research Society International World Congress on Osteoarthritis, Liverpool, UK. April 26^th – 29^th, 2018.
• Hubley-Kozey CL, Costello KE, Hatfield GL, Ikeda DM, Stanish WD, Astephen Wilson JL. The association between knee joint muscle activation and knee joint moment patterns during walking in moderate medial compartment knee osteoarthritis: implications for intervention. Osteoarthritis Research Society International World Congress on Osteoarthritis, Liverpool, UK. April 26^th – 29^th, 2018.

2017 and earlier

• Costello KE, Astephen Wilson JL, Stanish WD, Hubley-Kozey CL. Does 30 minutes of continuous walking induce gait pattern changes linked to osteoarthritis progression? Osteoarthritis Research Society International World Congress on Osteoarthritis, Las Vegas, NV, USA. April 27^th – 30^th, 2017.
• Costello KE, Astephen Wilson JL, Stanish WD, Hubley-Kozey CL. Stiff gait pattern linked to reduced intensity but not total physical activity in knee osteoarthritis. 19^th Biennial Meeting of the Canadian Society for Biomechanics, Hamilton, Ontario, Canada. July 19^th– 22^nd, 2016. [Finalist for CSB/NDI doctoral award]
• Costello KE, Astephen Wilson JL, Urquhart N, Stanish WD, Hubley-Kozey CL. Gait biomechanics predict structural progression of knee osteoarthritis. 19^th Biennial Meeting of the Canadian Society for Biomechanics, Hamilton, ON, Canada. July 19^th– 22^nd, 2016.
• Astephen Wilson JL, Ikeda DM, Costello KE, Stanish WD, Hubley-Kozey CL. Baseline differences in knee flexion angle and rotation moment during walking gait are associated with radiographic knee osteoarthritis progression at three years. 19^th Biennial Meeting of the Canadian Society for Biomechanics, Hamilton, ON, Canada. July 19^th– 22^nd, 2016.
• Costello KE, Hubley-Kozey CL, Astephen Wilson JL. Is the resultant moment a more sensitive metric of structural osteoarthritis progression than individual moments? 25^th Congress of the International Society of Biomechanics, Glasgow, UK. July 12^th-16^th, 2015.
• Hubley-Kozey CL, Astephen Wilson JL, Costello KE, Stanish WD. Biomechanical and neuromuscular alterations in knee osteoarthritis and asymptomatic controls: a longitudinal study. Osteoarthritis Research Society International World Congress on Osteoarthritis, Seattle, WA, USA. April 30^th – May 3^rd, 2015.
• Astephen Wilson JL, Ikeda DM, Costello KE, Stanish WD, Kozey CL. Biomechanical and neuromuscular longitudinal changes at 2.5-3 years with and without knee osteoarthritis. Osteoarthritis Research Society International World Congress on Osteoarthritis, Seattle, WA, USA. April 30^th – May 3^rd, 2015.
• Costello KE, Ikeda DM, Hatfield GL, Astephen Wilson JL, Stanish WD, Hubley-Kozey CL. Three-dimensional biomechanical differences between those with moderate osteoarthritis who progress radiographically versus those who do not. World Congress of Biomechanics, Boston, Massachusetts, USA. July 6^th – 11^th, 2014.
• Hubley-Kozey CL, Costello KE, Hatfield GL, Astephen Wilson JL, Stanish WD. Baseline three-dimensional knee joint biomechanics and muscle activation patterns differ between those with moderate OA who have radiographic progression versus those who do not. Osteoarthritis Research Society International World Congress on Osteoarthritis, Paris, France. April 24^th – 27^th, 2014.
• Wilson KJ, Giphart JE, Costello KE, Decker MJ, Souza BGS, Philippon MJ. Hip and pelvic kinematics in FAI patients differs between constrained and unconstrained squatting. 9^th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine Congress, Toronto, ON, Canada. May 12^th – 16^th, 2013.
• Wijdicks CA, Philippon MJ, Civitarese D, Costello KE, Wages JJ, Giphart JE, LaPrade RF. Hip kinematics in ice hockey goaltenders performing a butterfly motion and the effects of a mandated change in goalie pad width. Orthopaedic Research Society Annual Meeting 2013, San Antonio, TX, USA. January 26^th – 29^th, 2013.
• Matrangola SL, Costello KE, Madigan ML. Obesity does not influence the ability of young adults to recover balance from a forward fall with a single step. The 35^th Annual Meeting of the American Society of Biomechanics, Long Beach, CA, USA. August 10^th – 13^th, 2011.
• Matrangola SL, Costello KE, Madigan ML. The influence of obesity on single step balance recovery is dependent on perturbation characteristics. 8^th Annual Human Movement Science Research Symposium, Chapel Hill, NC, USA. February 25^th, 2011.
• Costello KE, Matrangola SL, Madigan ML. The effect of increased inertia on standing balance and balance recovery. Biomedical Engineering Society Annual Meeting, Austin, TX, USA. October 6^th – 9^th, 2010.
• Costello KE, Matrangola SL, Madigan ML. The effect of increased inertia on balance using an ankle strategy. The 34^th Annual Meeting of the American Society of Biomechanics, Providence, RI, USA. August 18^th – 21^st, 2010.
• Griffin TM, Costello KE, Setton LA, Guilak F. Locomotor compensation in a mouse model of musculoskeletal degeneration. 2008 American Physiological Society Intersociety Meeting: The Integrative Biology of Exercise – V, Hilton-Head, SC, USA. September 24^th – 27^th, 2008.
• Costello KE. How participation in activities such as Engineers Without Borders prepares students for their future careers. Engineers Without Borders – USA 2008 Annual International Conference, Seattle, WA, USA. March 27^th – 30^th, 2008.
• Abram B, Costello KE, Pearson L, Wen Y, Yamanaka Y. Future leaders working on present issues: undergraduate involvement in international development. International Association for the Exchange of Students for Technical Experience United States National Conference, Washington, D.C., USA. February 8^th – 11^th, 2007.